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| Acanthosis Nigricans |
Acanthosis nigricans (AN) is a skin disorder characterized by abnormally increased coloration (hyper pigmentation) and "velvety" thickening (hyperkeratosis) of the skin, particularly of skin fold regions, such as of the neck and groin and under the arms (axillae). Various benign (non-cancerous) forms of AN have been identified in which the disorder may be inherited as a primary condition or associated with various underlying syndromes; an excess accumulation of body fat (obesity); or the use of certain medications (i.e., drug-induced AN). In other instances, AN may occur in association with an underlying cancerous tumor (i.e., malignant AN).
Experts suggest that AN may be a skin manifestation of insulin resistance, which is a condition characterized by impaired biological responses to insulin. Insulin, a hormone produced by the pancreas, regulates blood glucose levels by promoting the movement of glucose into cells for energy production or into the liver and fat cells for storage. (Glucose is a simple sugar that is the body's primary source of energy for cell metabolism.) Insulin resistance may be associated with various disorders, including obesity and non-insulin-dependent (type II) diabetes mellitus. In individuals with type II diabetes mellitus, the pancreas produces insulin but the body becomes resistant to its effects, leading to insufficient absorption of glucose and abnormally increased glucose levels in the blood (hyperglycemia) and urine. As a result, there may be a gradual onset of certain symptoms, including excessive urination (polyuria) and increased thirst (polydipsia), and the development of particular complications without appropriate treatment.
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Remedy |
Characteristics Symptoms |
Patient Worse by |
Patient Better by |
| Sepia |
Weariness and misery Weakness, yellow complexion,
bearing-down sensation,
Upward tendency of its symptoms
Easy fainting
"Ball" sensation in inner parts
Acts best on brunettes
Feels cold even in warm room
Feeling of goneness; not relieved by eating
Everything tastes too salty
Longing for vinegar, acids, and pickles
Loathes fat
Red, adhesive, sand in urine.
Leucorrhœa yellow, greenish; with much itching |
Forenoons and evenings Washing
Laundry-work
Dampness
Left side
After sweat
Cold air
Before thunder-storm
After milk, especially when boiled |
By exercise Pressure
Warmth of bed
Hot applications
Drawing limbs up
Cold bathing
After sleep |
| Antimonium Crudum |
Excessive irritability and fretfulness A
thickly-coated white tongue
Cannot bear heat of sun
Tendency to grow fat
No thirst; thirst in evening and night.
Loss of appetite
Desire for acids, pickles
Urine frequent, with burning, and backache; turbid and foul odor
Menses too early and profuse
Leucorrhœa watery; acrid, lumpy
Thick, hard, honey-colored scabs |
In evening From heat
Acids
Wine
Water
Washing
Wet poultices
By cold bathing |
In open air During rest
Moist warmth |
| Lachesis |
When the system is thoroughly poisoned and the
prostration is profound Very important during the climacteric and for
patients of a melancholic disposition
Sensation of tension in various parts
Cannot bear anything tight anywhere
Craving for alcohol, oysters
Any food causes distress
Hungry, cannot wait for food
Menses too short, too feeble; pains all relieved by the flow
Intense excitement of sexual organs
Patient sleeps into an aggravation
Sudden starting when falling asleep
Sleepiness, yet cannot sleep
Wide-awake in evening
Skin hot perspiration, bluish, purplish appearance |
After sleep Sleeps into aggravation
Left side
In the spring
Warm bath
Pressure or constriction
Hot drinks
Closing eyes |
Appearance of discharges Warm applications |
| Lycopodium |
Is adapted more especially to ailments gradually
developing Atony
Suits older persons, where the skin shows yellowish spots, earthy
complexion, uric acid diathesis, etc; also precocious, weakly children
Intolerant of cold drinks; craves everything warm
Best adapted to persons intellectually keen, but of weak, muscular power
Emaciation
Debility in morning
Pre-senility
is thin, withered, full of gas and dry
Lacks vital heat; has poor circulation, cold extremities
Pains come and go suddenly
Sensitive to noise and odors
Dyspepsia due to farinaceous and fermentable food, cabbage, beans, etc
Excessive hunger
Aversion to bread, etc
Desire for sweet things
Food tastes sour
Sour eructations
Eating ever so little creates fullness
Cannot eat oysters
Rolling of flatulence
Wakes at night feeling hungry
Incomplete burning eructations rise only to pharynx there burn for
hours
Likes to take food and drink hot
Polyuria during the night; heavy red sediment
No erectile power; impotence; premature emission
Menses too late; last too long, too profuse.
Leucorrhœa, acrid, with burning in vagina
Drowsy during day
Starting in sleep
Dreams of accidents
Painful callosities on soles
Skin becomes thick and indurated |
Right side From right to left
From above downward
4 to 8 pm
From heat or warm room, hot air, bed
Warm applications, except throat and stomach which are better from warm
drinks |
By motion After midnight
From warm food and drink
On getting cold
From being uncovered |
| Arsenicum Album |
All-prevailing debility, exhaustion, and
restlessness, with nightly aggravation Great exhaustion
after the slightest exertion
Irritable weakness
Burning pains.
Burning relieved by heat
Fear fright and worry
Septic infections and low vitality
Cannot bear the sight or smell of food
Great thirst; drinks much, but little at a time
Craves milk, acids and coffee
Stool small, offensive, dark, with much prostration
Urine scanty, burning, involuntary; albuminous
Menses too profuse and too soon.
Leucorrhœa, acrid, burning, offensive, thin
Sleep disturbed, anxious, restless; must have head raised by
pillows
Suffocative fits during sleep
Sleeps with hands over head
Dreams are full of care and fear |
Wet weather After midnight
From cold, cold drinks, or food
Seashore
Right side |
From heat From head elevated
Warm drinks |
| Dulcamara |
Hot days and cold nights towards the close of
summer are especially favorable to the action of Dulcamara Results from
sitting on cold, damp ground
Icy coldness
Patients living or working in damp, cold basements
Aversion to food
Burning thirst for cold drinks
Must urinate when getting chilled |
At night From cold in general
Damp, rainy weather |
From moving about External warmth |
| Sulphur |
Inertia and relaxation of fiber; hence feebleness
of tone characterizes its symptoms Ebullitions of heat, dislike of
water, dry and hard hair and skin, red orifices, sinking feeling at stomach
about 11 am, and cat-nap sleep
Dirty, filthy people, prone to skin affections
Aversion to being washed
When carefully-selected remedies fail to act, especially in acute
diseases,
Complaints that relapse
General offensive character of discharge and exhalations
Putrid eructation
Food tastes too salty
Drinks much, eats little
Milk disagrees
Great desire for sweets
Great acidity, sour eructation
Very weak and faint about 11 am; must have something to eat
Frequent micturition, especially at night
Must hurry, sudden call to urinate
Great quantities of colorless urine
Menses too late, short, scanty, and difficult; thick, black, acrid,
making parts sore.
Leucorrhœa, burning, excoriating
Talks, jerks, and twitches during sleep
Vivid dreams
Wakes up singing
Wakes frequently, and becomes wide awake suddenly
Catnaps; slightest noise awakens
Cannot sleep between 2 an 5 am |
At rest When standing
Warmth in bed
Washing
Bathing
In morning
11 am
Night
From alcoholic stimulants
Periodically |
Dry, warm weather Lying on right side
From drawing up affected limbs |
| Calcarea Carbonica |
Increased local and general perspiration Gets out
of breath easily
A jaded state, mental or physical, due to overwork
Easy relapses, interrupted convalescence
Great sensitiveness to cold; partial sweats
Children crave eggs and eat dirt and other indigestible things; are prone
to diarrhœa
Calcarea patient is fat, fair, flabby and perspiring and cold, damp and
sour
Aversion to meat, boiled things; craving for indigestible
things-chalk, coal, pencils; also for eggs, salt and sweets
Milk disagrees
Frequent sour eructations; sour vomiting
Dislike of fat
Loss of appetite when overworked
Heartburn and loud belching
Ravenous hunger.
Repugnance to hot food
Thirst; longing for cold drinks
Frequent emissions; increased desire; semen emitted too soon
Coition followed by weakness and irritability
Menses too early, too profuse, too long, with vertigo, toothache
and cold, damp feet; the least excitement causes their return
Leucorrhœa, milky
Ideas crowding in her mind prevent sleep; horrid visions when opening
eyes; starts at every noise; fears that she will go crazy
Drowsy in early part of evening
Frequent waking at night
Same disagreeable idea always arouses from light slumber
Night terrors
Dreams of the dead |
From exertion, mental or physical Ascending
Cold in every form
Water, washing, moist air, wet weather
During full moon
Standing
While eating |
Dry climate and weather Lying on painful side |
| Graphites |
Especially active in patients who are rather stout,
of fair complexion, with tendency to skin affections and constipation,
fat, chilly, and costive, with delayed menstrual history, take cold
easily Children impudent, teasing, laugh at reprimands
Has a particular tendency to develop the skin phase of internal disorders
Tendency to obesity
Gushing leucorrhœa
Induration of tissue
Breath smells like urine
Sour eructations
Aversion to meat
Sweets nauseate
Hot drinks disagree
Eructation difficult
Flatulence
Urine turbid, with sediment; sour smelling
Menses too late, with constipation; pale and scanty, with tearing
pain in epigastrium, and itching before.
Leucorrhœa, pale, thin, profuse, white, excoriating, with
great weakness in back
Sexual debility, with increased desire; aversion to coition
Skin rough, hard, persistent dryness of portions of skin
unaffected by eczema |
Warmth At night
During and after menstruation |
In the dark From wrapping up |
| Phosphorus |
Tall, slender persons, narrow chested, with thin,
transparent skin, weakened by loss of animal fluids, with great nervous
debility, emaciation, amative tendencies Great susceptibility to external
impressions, to light, sound, odors, touch, electrical changes,
thunder-storms
Suddenness of symptoms, sudden prostration, faints, sweats,
shooting pains, etc
Thirst for very cold water
Hunger soon after eating
Sour taste and sour eructations after every meal
Belching large quantities of wind, after eating
Stool very fetid stools and flatus; long, narrow,
hard, like a dog's; difficult to expel
Lack of power; irresistible desire; involuntary emissions, with
lascivious dreams
Menses too early and scanty-not profuse, but last too long
Weeps before menses
Leucorrhœa profuse, smarting, corrosive, instead of menses
Great drowsiness, especially after meals
Vivid dreams of fire; of hæmorrhage
Lascivious dreams
Goes to sleep late and awakens weak
Short naps and frequent wakings |
Touch Physical or mental exertion
Twilight
Warm food or drink
Change of weather
From getting wet in hot weather
Evening
Lying on left or painful side
During a thunder-storm
Ascending stairs |
In dark Lying on right side
Cold food
Cold
Open air
Washing with cold water
Sleep |
| Thuja |
Hydrogenoid constitutions, whose blood is
morbidly hydroscopic, so that damp air and water are inimical. Rapid
exhaustion and emaciation
Chilly
Complete loss of appetite
Dislike for fresh meat and potatoes
Rancid eructations after fat food
Cannot eat onions
Urinary stream split and small
Sensation of trickling after urinating
Desire to urinate sudden and urgent, but cannot be controlled
Profuse leucorrhœa; thick, greenish.
Menses scanty, retarded |
At night From heat of bed
At 3 am and 3 pm
From cold, damp air
After breakfast
Fat
Coffee
Vaccination |
Left side While drawing up a limb |
| Ammonium Carbonicum |
Suits rather stout women who are always tired and
weary, take cold easily, suffer from cholera-like symptoms before menses,
lead a sedentary life, have a slow reaction generally, and are disposed to
frequent use of the smelling-bottle Fat patients with weak heart,
wheezing, feel suffocated
Very sensitive to cold air
Great aversion to water; cannot bear to touch it
Heaviness in all organs
Uncleanness in bodily habits
Acid secretions
Prostration from trifles
Great appetite, but easily satisfied
Stools difficult, hard, and knotty
Frequent desire to urinate; involuntary at night
Erection without desire
Leucorrhœa burning, acrid, watery
Aversion to the other sex
Menses too frequent, profuse, early, copious, clotted, black;
colicky pains, and hard, difficult stool, with fatigue, especially of
thighs; yawning and chilliness
Sleepiness during the day; starts from sleep strangling |
Evenings From cold, wet weather
Wet applications
Washing
During 3 to 4 am
During menses |
Lying on painful side and on stomach In dry
weather |
| Borax |
Salivation Dread of downward motion
Leucorrhœa like white of eggs, with sensation as if warm water was
flowing
Menses too soon, profuse, with griping, nausea and pain in stomach
extending into small of back
Voluptuous dreams
Cannot sleep on account of heat, especially in head
Cries out of sleep as if frightened |
Downward motion Noise
Smoking
Warm weather
After menses |
Pressure Evening
Cold weather |
| Kali Carbonicum |
Soft pulse, coldness, general depression, and very
characteristic stitches Sensitive to every atmospheric change
Intolerance of cold weather
Fleshy aged people, with dropsical and paretic tendencies
Sweat, backache, and weakness.
"Giving-out" sensation
Flatulence
Desire for sweets
Sour eructations
Disgust for food
Obliged to rise several times at night to urinate
Deficient sexual instinct
Excessive emissions, followed by weakness
Drowsy after eating
Wakes about two o'clock and cannot sleep again |
After coition In cold weather
From soup and coffee
In morning about three o'clock
Lying on left and painful side |
In warm weather Though moist
During day
While moving about |
| Silicea |
Increased susceptibility to nervous stimuli and
exaggerated reflexes Keloid growth
Scrofulous, rachitic children, with large head open fontanelles and
sutures, distended abdomen, slow in walking
Ill effects of vaccination
Suppurative processes
Is cold, chilly, hugs the fire, wants plenty warm clothing, hates drafts,
hands and feet cold, worse in winter
Lack of vital heat
Prostration of mind and body
Great sensitiveness to taking cold
Intolerance of alcoholic stimulants
Want of grit, moral or physical
Disgust for meat and warm food
Want of appetite; thirst excessive
Sour eructations after eating
A milky, acrid leucorrhœa, during urination
Discharge of blood between menstrual periods
Increased menses, with paroxysms of icy coldness over whole body
Sleeplessness, with great orgasm of blood and heat in head
Frequent starts in sleep
Anxious dreams |
New moon In morning
From washing
During menses
Uncovering
Lying down
Damp
Lying on left side
Cold |
Warmth Wrapping up head
Summer
In wet or humid weather |
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